Optimization of human interferon beta protein expression in Chinese hamster ovary cells
Background and aims: Human interferon beta-1a (hIFNβ-1a) is a 22.5-kDa glycoprotein used to treat diseases such as multiple sclerosis (MS). Because of appropriate post-translation modifications, protein isolation, and lack of toxicity in Chinese hamster ovary (CHO) cells, we cloned hIFNβ-1a encoding...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Shahrekord University of Medical Sciences
2021-06-01
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Series: | Journal of Shahrekord University of Medical Sciences |
Subjects: | |
Online Access: | http://j.skums.ac.ir/PDF/jskums-23-68.pdf |