Novel nanoadjuvants balance immune activation with modest inflammation: implications for older adult vaccines

Abstract Background Age-associated impairments of immune response and inflammaging likely contribute to poor vaccine efficacy. An appropriate balance between activation of immune memory and inflammatory response may be more effective in vaccines for older adults; attempts to overcome reduced efficac...

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Bibliographic Details
Main Authors: Kathleen A. Ross, April M. Tingle, Sujata Senapati, Kaitlyn G. Holden, Michael J. Wannemuehler, Surya K. Mallapragada, Balaji Narasimhan, Marian L. Kohut
Format: Article
Language:English
Published: BMC 2023-06-01
Series:Immunity & Ageing
Subjects:
Online Access:https://doi.org/10.1186/s12979-023-00349-5