Novel nanoadjuvants balance immune activation with modest inflammation: implications for older adult vaccines
Abstract Background Age-associated impairments of immune response and inflammaging likely contribute to poor vaccine efficacy. An appropriate balance between activation of immune memory and inflammatory response may be more effective in vaccines for older adults; attempts to overcome reduced efficac...
Main Authors: | Kathleen A. Ross, April M. Tingle, Sujata Senapati, Kaitlyn G. Holden, Michael J. Wannemuehler, Surya K. Mallapragada, Balaji Narasimhan, Marian L. Kohut |
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Format: | Article |
Language: | English |
Published: |
BMC
2023-06-01
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Series: | Immunity & Ageing |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12979-023-00349-5 |
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