Targeting General Transcriptional Machinery as a Therapeutic Strategy for Adult T-Cell Leukemia

Cancer cells are highly reliant on certain molecular pathways, which support their survival and proliferation. The fundamental concept of molecularly targeted therapy is to target a protein that is specifically deregulated or overexpressed in cancer cells. However, drug resistance and tumor heteroge...

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Bibliographic Details
Main Authors: Regina Wan Ju Wong, Takashi Ishida, Takaomi Sanda
Format: Article
Language:English
Published: MDPI AG 2018-05-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/23/5/1057