The Role of PARPs in Inflammation—And Metabolic—Related Diseases: Molecular Mechanisms and Beyond

The Role of PARPs in Inflammation—And Metabolic—Related Diseases: Molecular Mechanisms and Beyond

Poly(ADP-ribosyl)ation (PARylation) is an essential post-translational modification catalyzed by poly(ADP-ribose) polymerase (PARP) enzymes. Poly(ADP-ribose) polymerase 1 (PARP1) is a well-characterized member of the PARP family. PARP1 plays a crucial role in multiple biological processes and PARP1...

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Bibliographic Details
Main Authors: Yueshuang Ke, Chenxin Wang, Jiaqi Zhang, Xiyue Zhong, Ruoxi Wang, Xianlu Zeng, Xueqing Ba
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Cells
Subjects:
poly(ADP)-ribosylation
PARP1
cancer
inflammation
metabolism
therapeutic approaches
Online Access:https://www.mdpi.com/2073-4409/8/9/1047

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https://www.mdpi.com/2073-4409/8/9/1047

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