Multiple kinesins induce tension for smooth cargo transport

Multiple kinesins induce tension for smooth cargo transport

How cargoes move within a crowded cell—over long distances and at speeds nearly the same as when moving on unimpeded pathway—has long been mysterious. Through an in vitro force-gliding assay, which involves measuring nanometer displacement and piconewtons of force, we show that multiple mammalian ki...

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Bibliographic Details
Main Authors: Marco Tjioe, Saurabh Shukla, Rohit Vaidya, Alice Troitskaia, Carol S Bookwalter, Kathleen M Trybus, Yann R Chemla, Paul R Selvin
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-10-01
Series:eLife
Subjects:
kinesin
recombinant
sf9 cell purification
multiple motors
microtubules
Online Access:https://elifesciences.org/articles/50974

Internet

https://elifesciences.org/articles/50974

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