Multiple kinesins induce tension for smooth cargo transport
How cargoes move within a crowded cell—over long distances and at speeds nearly the same as when moving on unimpeded pathway—has long been mysterious. Through an in vitro force-gliding assay, which involves measuring nanometer displacement and piconewtons of force, we show that multiple mammalian ki...
Main Authors: | Marco Tjioe, Saurabh Shukla, Rohit Vaidya, Alice Troitskaia, Carol S Bookwalter, Kathleen M Trybus, Yann R Chemla, Paul R Selvin |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2019-10-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/50974 |
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