Geometrical and thermodynamic stability of govaniadine scaffold adducts with dopamine receptor D1

Geometrical and thermodynamic stability of govaniadine scaffold adducts with dopamine receptor D1

Govaniadine, an isoquinoline alkaloid first isolated from Corydalis govaniana Wall., has been reported to possess multiple biological properties. Its potential as a possible dopamine receptor D1 modulator has been assessed in this research work along with its 3D similar structures for hit molecule o...

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Bibliographic Details
Main Authors: Ram Lal Swagat Shrestha, Binita Maharjan, Timila Shrestha, Bishnu Prasad Marasini, Jhashanath Adhikari Subin
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Results in Chemistry
Subjects:
Free energy
MMGBSA
Molecular docking
Molecular dynamics
Natural product
Phytochemical
Online Access:http://www.sciencedirect.com/science/article/pii/S2211715624000596

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http://www.sciencedirect.com/science/article/pii/S2211715624000596

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