Maternal immune activation induces autism-like changes in behavior, neuroinflammatory profile and gut microbiota in mouse offspring of both sexes

Abstract Autism Spectrum Disorder (ASD) is a sex-biased neurodevelopmental disorder with a male to female prevalence of 4:1, characterized by persistent deficits in social communication and interaction and restricted-repetitive patterns of behavior, interests or activities. Microbiota alterations as...

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Bibliographic Details
Main Authors: Anna Maria Tartaglione, Annacandida Villani, Maria Antonietta Ajmone-Cat, Luisa Minghetti, Laura Ricceri, Valerio Pazienza, Roberta De Simone, Gemma Calamandrei
Format: Article
Language:English
Published: Nature Publishing Group 2022-09-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-022-02149-9