Model-Based Optimization of Solid-Supported Micro-Hotplates for Microfluidic Cryofixation

Cryofixation by ultra-rapid freezing is widely regarded as the gold standard for preserving cell structure without artefacts for electron microscopy. However, conventional cryofixation technologies are not compatible with live imaging, making it difficult to capture dynamic cellular processes at a p...

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Bibliographic Details
Main Authors: Daniel B. Thiem, Greta Szabo, Thomas P. Burg
Format: Article
Language:English
Published: MDPI AG 2024-08-01
Series:Micromachines
Subjects:
Online Access:https://www.mdpi.com/2072-666X/15/9/1069