Host cell cAMP-Epac-Rap1b pathway inhibition by hawthorn extract as a potential target against Trypanosoma cruzi infection

Although the two drugs currently available for the treatment of Chagas disease, Benznidazole and Nifurtimox, have proven to be effective in the acute phase of the disease, the 60–90-day treatment leads to high toxicity and unwanted side effects, presenting, in addition, a low efficacy in the chronic...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Gabriel Ferri, Lucía R. Fernández, Guillermo Di Mario, Daniel Musikant, Jorge A. Palermo, Martin M. Edreira
Формат: Өгүүллэг
Хэл сонгох:English
Хэвлэсэн: Frontiers Media S.A. 2023-12-01
Цуврал:Frontiers in Microbiology
Нөхцлүүд:
Онлайн хандалт:https://www.frontiersin.org/articles/10.3389/fmicb.2023.1301862/full