Pathway elucidation of bioactive rhamnosylated ginsenosides in Panax ginseng and their de novo high-level production by engineered Saccharomyces cerevisiae

A key missing enzyme in the plant Panax ginseng Rg2 and Re2 ginsenoside biosynthesis pathway is identified, and its expression is engineered in yeast for high-level production.

Bibliographic Details
Main Authors: Chaojing Li, Xing Yan, Zhenzhen Xu, Yan Wang, Xiao Shen, Lei Zhang, Zhihua Zhou, Pingping Wang
Format: Article
Language:English
Published: Nature Portfolio 2022-08-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-022-03740-y