Specification of neural circuit architecture shaped by context-dependent patterned LAR-RPTP microexons

Abstract LAR-RPTPs are evolutionarily conserved presynaptic cell-adhesion molecules that orchestrate multifarious synaptic adhesion pathways. Extensive alternative splicing of LAR-RPTP mRNAs may produce innumerable LAR-RPTP isoforms that act as regulatory “codes” for determining the identity and str...

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Bibliographic Details
Main Authors: Kyung Ah Han, Taek-Han Yoon, Jinhu Kim, Jusung Lee, Ju Yeon Lee, Gyubin Jang, Ji Won Um, Jong Kyoung Kim, Jaewon Ko
Format: Article
Language:English
Published: Nature Portfolio 2024-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-45695-0