A cytokine-induced spheroid-based in vitro model for studying osteoarthritis pathogenesis

A cytokine-induced spheroid-based in vitro model for studying osteoarthritis pathogenesis

Given the lack of in vitro models faithfully reproducing the osteoarthritis (OA) disease on-set, this work aimed at manufacturing a reliable and predictive in vitro cytokine-based Articular Cartilage (AC) model to study OA progression. Cell spheroids of primary human fetal chondrocytes (FCs) and h-T...

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Bibliographic Details
Main Authors: Annachiara Scalzone, Giorgia Cerqueni, Xiao Nong Wang, Kenny Dalgarno, Monica Mattioli-Belmonte, Ana M. Ferreira-Duarte, Piergiorgio Gentile
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
in vitro model
articular cartilage
osteoarthritis
cytokines
chondrocytes
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2023.1167623/full

Internet

https://www.frontiersin.org/articles/10.3389/fbioe.2023.1167623/full

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