Inability of Low Oxygen Tension to Induce Chondrogenesis in Human Infrapatellar Fat Pad Mesenchymal Stem Cells

Inability of Low Oxygen Tension to Induce Chondrogenesis in Human Infrapatellar Fat Pad Mesenchymal Stem Cells

ObjectiveArticular cartilage of the knee joint is avascular, exists under a low oxygen tension microenvironment, and does not self-heal when injured. Human infrapatellar fat pad-sourced mesenchymal stem cells (IFP-MSC) are an arthroscopically accessible source of mesenchymal stem cells (MSC) for the...

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Bibliographic Details
Main Authors: Samia Rahman, Alexander R. A. Szojka, Yan Liang, Melanie Kunze, Victoria Goncalves, Aillette Mulet-Sierra, Nadr M. Jomha, Adetola B. Adesida
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
chondrogenesis
adipose tissue
human mesenchymal stem cells
oxygen tension
xenograft
in vivo calcification
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.703038/full

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https://www.frontiersin.org/articles/10.3389/fcell.2021.703038/full

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