Comparative anatomy of chromosomal domains with imprinted and non-imprinted allele-specific DNA methylation.

Comparative anatomy of chromosomal domains with imprinted and non-imprinted allele-specific DNA methylation.

Allele-specific DNA methylation (ASM) is well studied in imprinted domains, but this type of epigenetic asymmetry is actually found more commonly at non-imprinted loci, where the ASM is dictated not by parent-of-origin but instead by the local haplotype. We identified loci with strong ASM in human t...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Anupam Paliwal, Alexis M Temkin, Kristi Kerkel, Alexander Yale, Iveta Yotova, Natalia Drost, Simon Lax, Chia-Ling Nhan-Chang, Charles Powell, Alain Borczuk, Abraham Aviv, Ronald Wapner, Xiaowei Chen, Peter L Nagy, Nicholas Schork, Catherine Do, Ali Torkamani, Benjamin Tycko
Format: Artikel
Sprache:English
Veröffentlicht: Public Library of Science (PLoS) 2013-08-01
Schriftenreihe:PLoS Genetics
Online Zugang:http://europepmc.org/articles/PMC3757050?pdf=render

Online

http://europepmc.org/articles/PMC3757050?pdf=render

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