AHNAK suppresses tumour proliferation and invasion by targeting multiple pathways in triple-negative breast cancer

AHNAK suppresses tumour proliferation and invasion by targeting multiple pathways in triple-negative breast cancer

Abstract Background AHNAK, also known as desmoyokin, is a giant protein with the molecular size of approximately 700 kDa and exerts diverse functions in different types of cancer. Results In the present study, we demonstrated that AHNAK mRNA levels were down-regulated in 7 out of 8 human breast canc...

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Bibliographic Details
Main Authors: Bo Chen, Jin Wang, Danian Dai, Qingyu Zhou, Xiaofang Guo, Zhi Tian, Xiaojia Huang, Lu Yang, Hailin Tang, Xiaoming Xie
Format: Article
Language:English
Published: BMC 2017-05-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
AHNAK
Triple-negative breast cancer
AKT
MAPK
Wnt/β-catenin pathway
Online Access:http://link.springer.com/article/10.1186/s13046-017-0522-4

Internet

http://link.springer.com/article/10.1186/s13046-017-0522-4

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