Design, synthesis and antiviral activities of chalcone derivatives containing pyrimidine

Design, synthesis and antiviral activities of chalcone derivatives containing pyrimidine

A series of chalcone derivatives (T1-T23) containing pyrimidine were synthesized, characterized, and assessed for their antiviral activity against tobacco mosaic virus (TMV) activities. Most target compounds displayed better antiviral activities against TMV than commercial ningnanmycin. Among them,...

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Bibliographic Details
Main Authors: Wenliang Zhan, Piao Mao, Chunmei Yuan, Yuanquan Zhang, Tao Zhang, Yi Liu, Jiao Tian, Wei Xue
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Journal of Saudi Chemical Society
Subjects:
Chalcone
Pyrimidine
Antiviral activity
TMV-CP
Molecular docking
Online Access:http://www.sciencedirect.com/science/article/pii/S1319610322001727

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http://www.sciencedirect.com/science/article/pii/S1319610322001727

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