Isoflurane Post-conditioning Ameliorates Cerebral Ischemia/Reperfusion Injury by Enhancing Angiogenesis Through Activating the Shh/Gli Signaling Pathway in Rats

Isoflurane Post-conditioning Ameliorates Cerebral Ischemia/Reperfusion Injury by Enhancing Angiogenesis Through Activating the Shh/Gli Signaling Pathway in Rats

Background: Stroke is the second leading cause of death worldwide. Angiogenesis facilitates the formation of microvascular networks and promotes recovery after stroke. The Shh/Gli signaling pathway is implicated in angiogenesis and cerebral ischemia-reperfusion (I/R) injury. This study aimed at inve...

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Bibliographic Details
Main Authors: Li Peng, Jiangwen Yin, Mingyue Ge, Sheng Wang, Liping Xie, Yan Li, Jun-qiang Si, Ketao Ma
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Neuroscience
Subjects:
Sonic hedgehog
glioblastoma (Gli)
isoflurane
post-conditioning
angiogenesis
cerebral ischemia/reperfusion
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2019.00321/full

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https://www.frontiersin.org/article/10.3389/fnins.2019.00321/full

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