The Effect of the Topmost Layer and the Type of Bone Morphogenetic Protein-2 Immobilization on the Mesenchymal Stem Cell Response

The Effect of the Topmost Layer and the Type of Bone Morphogenetic Protein-2 Immobilization on the Mesenchymal Stem Cell Response

Recombinant human bone morphogenetic protein-2 (rhBMP-2) plays a key role in the stem cell response, not only via its influence on osteogenesis, but also on cellular adhesion, migration, and proliferation. However, when applied clinically, its supra-physiological levels cause many adverse effects. T...

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Bibliographic Details
Main Authors: Magdalena Wytrwal-Sarna, Małgorzata Sekuła-Stryjewska, Agata Pomorska, Ewa Ocłoń, Katarzyna Gajos, Michal Sarna, Ewa Zuba-Surma, Andrzej Bernasik, Krzysztof Szczubiałka
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:International Journal of Molecular Sciences
Subjects:
diazoresin
chondroitin sulfate
bone morphogenetic protein 2
TOF-SIMS
AR-XPS
cell culture surfaces
Online Access:https://www.mdpi.com/1422-0067/23/16/9287

Internet

https://www.mdpi.com/1422-0067/23/16/9287

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