Metabolic maturation of differentiating cardiosphere-derived cells

Metabolic maturation of differentiating cardiosphere-derived cells

Cardiosphere-derived cells (CDCs) can be expanded in vitro and induced to differentiate along the cardiac lineage. To recapitulate the phenotype of an adult cardiomyocyte, differentiating progenitors need to upregulate mitochondrial glucose and fatty acid oxidation. Here we cultured and differentiat...

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Bibliographic Details
Main Authors: Khadijeh Kathy Pakzad, Jun Jie Tan, Stephanie Anderson, Mary Board, Kieran Clarke, Carolyn A. Carr
Format: Article
Language:English
Published: Elsevier 2021-07-01
Series:Stem Cell Research
Subjects:
Extracellular matrix
Glycolytic metabolism
Oxidative phosphorylation
Cardiac progenitor cells
Cardiomyogenic differentiation
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506121002683

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http://www.sciencedirect.com/science/article/pii/S1873506121002683

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