A novel CpG ODN compound adjuvant enhances immune response to spike subunit vaccines of porcine epidemic diarrhea virus

A novel CpG ODN compound adjuvant enhances immune response to spike subunit vaccines of porcine epidemic diarrhea virus

CpG oligodeoxynucleotides (CpG ODNs) boost the humoral and cellular immune responses to antigens through interaction with Toll-like receptor 9 (TLR9). These CpG ODNs have been extensively utilized in human vaccines. In our study, we evaluated five B-type CpG ODNs that have stimulatory effects on pig...

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Bibliographic Details
Main Authors: Yating Wang, Shijia Liu, Boshuo Li, Xinyao Sun, Qi Pan, Yuxin Zheng, Jia Liu, Yongqiang Zhao, Jingyu Wang, Liming Liu, Enqi Du
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Immunology
Subjects:
PEDV
CpG ODN
subunit vaccine
compound adjuvant
immune response
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1336239/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2024.1336239/full

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