Tethering of Lsh at the Oct4 locus promotes gene repression associated with epigenetic changes

Lsh is a chromatin remodeling factor that regulates DNA methylation and chromatin function in mammals. The dynamics of these chromatin changes and whether they are directly controlled by Lsh remain unclear. To understand the molecular mechanisms of Lsh chromatin controlled regulation of gene express...

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Bibliographic Details
Main Authors: Jianke Ren, Nathaniel A. Hathaway, Gerald R. Crabtree, Kathrin Muegge
Format: Article
Language:English
Published: Taylor & Francis Group 2018-02-01
Series:Epigenetics
Subjects:
Online Access:http://dx.doi.org/10.1080/15592294.2017.1338234