Tethering of Lsh at the Oct4 locus promotes gene repression associated with epigenetic changes
Lsh is a chromatin remodeling factor that regulates DNA methylation and chromatin function in mammals. The dynamics of these chromatin changes and whether they are directly controlled by Lsh remain unclear. To understand the molecular mechanisms of Lsh chromatin controlled regulation of gene express...
Main Authors: | Jianke Ren, Nathaniel A. Hathaway, Gerald R. Crabtree, Kathrin Muegge |
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Format: | Article |
Language: | English |
Published: |
Taylor & Francis Group
2018-02-01
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Series: | Epigenetics |
Subjects: | |
Online Access: | http://dx.doi.org/10.1080/15592294.2017.1338234 |
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