Multifocal optical projection microscopy enables label-free 3D measurement of cardiomyocyte cluster contractility

Abstract Human induced pluripotent stem cell (hiPSC)-derived cardiomyocyte (CM) models have become an attractive tool for in vitro cardiac disease modeling and drug studies. These models are moving towards more complex three-dimensional microphysiological organ-on-chip systems. Label-free imaging-ba...

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Bibliographic Details
Main Authors: Birhanu Belay, Edite Figueiras, Jari Hyttinen, Antti Ahola
Format: Article
Language:English
Published: Nature Portfolio 2023-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-46510-4