Rapid detection of Mycobacterium tuberculosis DNA and genetic markers for Isoniazid resistance in Ziehl-Neelsen stained slides

Rapid detection of Mycobacterium tuberculosis DNA and genetic markers for Isoniazid resistance in Ziehl-Neelsen stained slides

BACKGROUND Early diagnosis of tuberculosis (TB) and identification of strains of Mycobacterium tuberculosis resistant to anti-TB drugs are considered the main factors for disease control. OBJECTIVES To standardise a real-time polymerase chain reaction (qPCR) assay technique and apply it to identi...

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Bibliographic Details
Main Authors: Graziele Lima Bello, Franciele Costa Leite Morais, Sheile Pinheiro de Jesus, Jonas Michel Wolf, Mirela Gehlen, Isabela Neves de Almeida, Lida Jouca de Assis Figueiredo, Tainá dos Santos Soares, Regina Bones Barcellos, Elis Regina Dalla Costa, Silvana Spíndola de Miranda, Maria Lucia Rosa Rossetti
Format: Article
Language:English
Published: Fundação Oswaldo Cruz (FIOCRUZ) 2020-04-01
Series:Memorias do Instituto Oswaldo Cruz
Subjects:
Mycobacterium tuberculosis
Isoniazid resistance
genotyping
real-time PCR
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762020000100309&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762020000100309&tlng=en

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