Intranasal COVID-19 vaccine induces respiratory memory T cells and protects K18-hACE mice against SARS-CoV-2 infection

Intranasal COVID-19 vaccine induces respiratory memory T cells and protects K18-hACE mice against SARS-CoV-2 infection

Abstract Current COVID-19 vaccines prevent severe disease, but do not induce mucosal immunity or prevent infection with SARS-CoV-2, especially with recent variants. Furthermore, serum antibody responses wane soon after immunization. We assessed the immunogenicity and protective efficacy of an experi...

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Bibliographic Details
Main Authors: Béré K. Diallo, Caitlín Ní Chasaide, Ting Y. Wong, Pauline Schmitt, Katherine S. Lee, Kelly Weaver, Olivia Miller, Melissa Cooper, Seyed D. Jazayeri, F. Heath Damron, Kingston H. G. Mills
Format: Article
Language:English
Published: Nature Portfolio 2023-05-01
Series:npj Vaccines
Online Access:https://doi.org/10.1038/s41541-023-00665-3

Internet

https://doi.org/10.1038/s41541-023-00665-3

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