The BTLA and PD‐1 signaling pathways independently regulate the proliferation and cytotoxicity of human peripheral blood γδ T cells

The BTLA and PD‐1 signaling pathways independently regulate the proliferation and cytotoxicity of human peripheral blood γδ T cells

Abstract Background B‐ and T‐lymphocyte attenuator (BTLA) and programmed cell death‐1 (PD‐1) inhibit γδ T cell homeostasis and activation. This study aimed to determine whether BTLA and PD‐1 signaling pathways were convergent or independent in human peripheral blood γδ T cells. Herein we demonstrate...

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Bibliographic Details
Main Authors: Hyun J. Hwang, Jae J. Lee, Sung H. Kang, Jin K. Suh, Eun S. Choi, Seongsoo Jang, Sang‐Hyun Hwang, Kyung‐Nam Koh, Ho J. Im, Nayoung Kim
Format: Article
Language:English
Published: Wiley 2021-03-01
Series:Immunity, Inflammation and Disease
Subjects:
AKT
BTLA
cytotoxicity
human peripheral blood γδ T cells
PD‐1
proliferation
Online Access:https://doi.org/10.1002/iid3.390

Internet

https://doi.org/10.1002/iid3.390

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