Saposin C, Key Regulator in the Alpha-Synuclein Degradation Mediated by Lysosome
Lysosomal dysfunction has been proposed as one of the most important pathogenic molecular mechanisms in Parkinson disease (PD). The most significant evidence lies in the <i>GBA</i> gene, which encodes for the lysosomal enzyme β-glucocerebrosidase (β-GCase), considered the main genetic ri...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2022-10-01
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| Series: | International Journal of Molecular Sciences |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1422-0067/23/19/12004 |