Galangin Reverses H<sub>2</sub>O<sub>2</sub>-Induced Dermal Fibroblast Senescence via SIRT1-PGC-1α/Nrf2 Signaling

Galangin Reverses H<sub>2</sub>O<sub>2</sub>-Induced Dermal Fibroblast Senescence via SIRT1-PGC-1α/Nrf2 Signaling

UV radiation and H<sub>2</sub>O<sub>2</sub> are the primary factors that cause skin aging. Both trigger oxidative stress and cellular aging. It has been reported that deacetylase silent information regulator 1 (SIRT1), a longevity gene, enhances activation of NF-E2-related fa...

Full description

Bibliographic Details
Main Authors: Jian-Jr Lee, Shang-Chuan Ng, Jia-Yun Hsu, Hsun Liu, Chih-Jung Chen, Chih-Yang Huang, Wei-Wen Kuo
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:International Journal of Molecular Sciences
Subjects:
SIRT1
PGC-1α
UVB
senescence
HS68 human dermal fibroblast cells
Online Access:https://www.mdpi.com/1422-0067/23/3/1387

Internet

https://www.mdpi.com/1422-0067/23/3/1387

Similar Items