Reduced Staphylococcus Abundance Characterizes the Lesional Microbiome of Actinic Keratosis Patients after Field-Directed Therapies

ABSTRACT Skin microbiome dysbiosis with a Staphylococcus overabundance is a feature of actinic keratosis (AK) and squamous skin carcinoma (SCC) patients. The impact of lesion-directed treatments for AK lesions such as diclofenac (DIC) and cold atmospheric plasma (CAP) on the lesional microbiome is n...

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Main Authors: Jan Kehrmann, Fiona Koch, Skrollan Zumdick, Anna Höwner, Lara Best, Lars Masshöfer, Sarah Scharfenberg, Michael Zeschnigk, Jürgen C. Becker, Dirk Schadendorf, Jan Buer, Alexander Roesch
Format: Article
Language:English
Published: American Society for Microbiology 2023-06-01
Series:Microbiology Spectrum
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Online Access:https://journals.asm.org/doi/10.1128/spectrum.04401-22