Endothelial leakiness elicited by amyloid protein aggregation

Abstract Alzheimer’s disease (AD) is a major cause of dementia debilitating the global ageing population. Current understanding of the AD pathophysiology implicates the aggregation of amyloid beta (Aβ) as causative to neurodegeneration, with tauopathies, apolipoprotein E and neuroinflammation consid...

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Bibliographic Details
Main Authors: Yuhuan Li, Nengyi Ni, Myeongsang Lee, Wei Wei, Nicholas Andrikopoulos, Aleksandr Kakinen, Thomas P. Davis, Yang Song, Feng Ding, David Tai Leong, Pu Chun Ke
Format: Article
Language:English
Published: Nature Portfolio 2024-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-44814-1