Astragalus Polysaccharide Alleviates Ulcerative Colitis by Regulating the Balance of mTh17/mTreg Cells through TIGIT/CD155 Signaling

Astragalus Polysaccharide Alleviates Ulcerative Colitis by Regulating the Balance of mTh17/mTreg Cells through TIGIT/CD155 Signaling

The balance between memory Th17 cells (mTh17) and memory Treg cells (mTreg) plays a key role in the pathogenesis of ulcerative colitis (UC), and TIGIT signaling is involved in the differentiation of mTh17/mTreg cells. Astragalus polysaccharide (APS) has good immunomodulatory and anti-inflammatory ef...

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Bibliographic Details
Main Authors: Qi Wan, Jiaqi Huang, Qiuping Xiao, Zeyun Zhang, Zheyan Zhang, Li Huang, Yifei Deng, Bailing Deng, Haimei Zhao, Youbao Zhong, Duanyong Liu
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Molecules
Subjects:
astragalus polysaccharide
colitis
mTh17/mTreg cells
TIGIT/CD155 signaling pathway
Online Access:https://www.mdpi.com/1420-3049/29/1/241

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https://www.mdpi.com/1420-3049/29/1/241

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