Causal effects of systemic inflammatory regulators on chronic kidney diseases and renal function: a bidirectional Mendelian randomization study

Causal effects of systemic inflammatory regulators on chronic kidney diseases and renal function: a bidirectional Mendelian randomization study

BackgroundWhile targeted systemic inflammatory modulators show promise in preventing chronic kidney disease (CKD) progression, the causal link between specific inflammatory factors and CKD remains uncertain.MethodsUsing a genome-wide association study of 41 serum cytokines from 8,293 Finnish individ...

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Bibliographic Details
Main Authors: Hongdian Li, Mingxuan Li, Cong Liu, Pengfei He, Ao Dong, Shaoning Dong, Mianzhi Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-08-01
Series:Frontiers in Immunology
Subjects:
chronic kidney disease
systemic inflammation
inflammatory modulators
Mendelian randomization
genetic causal association
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1229636/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1229636/full

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