The Impact of DNMT3A Status on NPM1 MRD Predictive Value and Survival in Elderly AML Patients Treated Intensively

The Impact of DNMT3A Status on NPM1 MRD Predictive Value and Survival in Elderly AML Patients Treated Intensively

Minimal residual disease (MRD) is now a powerful surrogate marker to assess the response to chemotherapy in acute myeloid leukemia (AML). <i>DNMT3A</i> mutation has been associated with adverse outcomes. In this study, we aimed to investigate the impact of <i>DNMT3A</i> statu...

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Bibliographic Details
Main Authors: Maël Heiblig, Nicolas Duployez, Alice Marceau, Delphine Lebon, Laure Goursaud, Isabelle Plantier, Laure Stalnikiewich, Nathalie Cambier, Marie Balsat, Gaëlle Fossard, Hélène Labussière-Wallet, Fiorenza Barraco, Sophie Ducastelle-Lepretre, Pierre Sujobert, Sarah Huet, Sandrine Hayette, Hervé Ghesquières, Xavier Thomas, Claude Preudhomme
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Cancers
Subjects:
acute myeloid leukemia
elderly
prognosis
<i>NPM1</i>
<i>DNMT3A</i>
Online Access:https://www.mdpi.com/2072-6694/13/9/2156

Internet

https://www.mdpi.com/2072-6694/13/9/2156

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