Effects of GRM4, SCN2A and SCN3B polymorphisms on antiepileptic drugs responsiveness and epilepsy susceptibility

Background: Pharmacotherapy of epilepsy including antiepileptic drugs (AEDs) is one of the main treatment approaches. As a biological target, sodium channels (Nav channels) and glutamate receptor genes are playing a major role in the etiology and treatment of epilepsy. Objective: This study aims to...

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Bibliographic Details
Main Authors: Laith N. AL-Eitan, Islam M. Al-Dalalah, Hanan A. Aljamal
Format: Article
Language:English
Published: Elsevier 2019-07-01
Series:Saudi Pharmaceutical Journal
Online Access:http://www.sciencedirect.com/science/article/pii/S131901641930057X