Age-related changes in the hematopoietic stem cell pool revealed via quantifying the balance of symmetric and asymmetric divisions.

Hematopoietic stem cells (HSCs) are somatic stem cells that continuously generate lifelong supply of blood cells through a balance of symmetric and asymmetric divisions. It is well established that the HSC pool increases with age. However, not much is known about the underlying cause for these obser...

Full description

Bibliographic Details
Main Authors: Teiko Kawahigashi, Shoya Iwanami, Munetomo Takahashi, Joydeep Bhadury, Shingo Iwami, Satoshi Yamazaki
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0292575