Impairments of cerebellar structure and function in a zebrafish KO of neuropsychiatric risk gene znf536

Abstract Genetic variants in ZNF536 contribute to the risk for neuropsychiatric disorders such as schizophrenia, autism, and others. The role of this putative transcriptional repressor in brain development and function is, however, largely unknown. We generated znf536 knockout (KO) zebrafish and stu...

Full description

Bibliographic Details
Main Authors: Tae-Yoon Kim, Arkaprava Roychaudhury, Hyun-Taek Kim, Tae-Ik Choi, Seung Tae Baek, Summer B. Thyme, Cheol-Hee Kim
Format: Article
Language:English
Published: Nature Publishing Group 2024-02-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-024-02806-1