LncRNA GACAT2 binds with protein PKM1/2 to regulate cell mitochondrial function and cementogenesis in an inflammatory environment

Abstract Periodontal ligament stem cells (PDLSCs) are a key cell type for restoring/regenerating lost/damaged periodontal tissues, including alveolar bone, periodontal ligament and root cementum, the latter of which is important for regaining tooth function. However, PDLSCs residing in an inflammato...

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Bibliographic Details
Main Authors: Xuan Li, Bei-Min Tian, Dao-Kun Deng, Fen Liu, Huan Zhou, De-Qin Kong, Hong-Lei Qu, Li-Juan Sun, Xiao-Tao He, Fa-Ming Chen
Format: Article
Language:English
Published: Nature Publishing Group 2022-03-01
Series:Bone Research
Online Access:https://doi.org/10.1038/s41413-022-00197-x