Up-Regulation of Na+/Ca2+ Exchange in Megakaryocytes Following TGFβ1 Treatment

Up-Regulation of Na+/Ca2+ Exchange in Megakaryocytes Following TGFβ1 Treatment

Background: Blood platelets are activated by increase of cytosolic Ca2+ activity ([Ca2+]i). Ca2+ entry is accomplished in part by store operated Ca2+ entry (SOCE) involving Ca2+ release activated Ca2+-channel (CRAC) moiety Orai1 and its regulator STIM1, which are stimulated by depletion of intracell...

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Bibliographic Details
Main Authors: Ahmad Almilaji, Jing Yan, Zohreh Hosseinzadeh, Evi Schmid, Meinrad Gawaz, Florian Lang
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2016-07-01
Series:Cellular Physiology and Biochemistry
Subjects:
Patch clamp
Cytosolic Ca2+
NCKX
NCX
Megakaryocytes
Online Access:http://www.karger.com/Article/FullText/445660

Internet

http://www.karger.com/Article/FullText/445660

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