Nuclear and cytoplasmic specific RNA binding proteome enrichment and its changes upon ferroptosis induction

Abstract The key role of RNA-binding proteins (RBPs) in posttranscriptional regulation of gene expression is intimately tied to their subcellular localization. Here, we show a subcellular-specific RNA labeling method for efficient enrichment and deep profiling of nuclear and cytoplasmic RBPs. A tota...

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Bibliographic Details
Main Authors: Haofan Sun, Bin Fu, Xiaohong Qian, Ping Xu, Weijie Qin
Format: Article
Language:English
Published: Nature Portfolio 2024-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-44987-9