Polycomb Repressive Complex 2 in Eukaryotes—An Evolutionary Perspective

Polycomb repressive complex 2 (PRC2) represents a group of evolutionarily conserved multi-subunit complexes that repress gene transcription by introducing trimethylation of lysine 27 on histone 3 (H3K27me3). PRC2 activity is of key importance for cell identity specification and developmental phase t...

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Bibliographic Details
Main Authors: Mallika Vijayanathan, María Guadalupe Trejo-Arellano, Iva Mozgová
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Epigenomes
Subjects:
Online Access:https://www.mdpi.com/2075-4655/6/1/3