METTL14 promotes prostate tumorigenesis by inhibiting THBS1 via an m6A-YTHDF2-dependent mechanism

Abstract N6-methyladenine (m6A) is the most predominant RNA modification, which has been shown to be related to many types of cancers. However, understanding of its role in prostate cancer (PCa) is largely unknown. Here, we report an upregulation of METTL14 that was correlated with poor prognosis in...

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Bibliographic Details
Main Authors: Yongjie Wang, Junfei Chen, Wei-Qiang Gao, Ru Yang
Format: Article
Language:English
Published: Nature Publishing Group 2022-03-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-022-00939-0