Loss of Elp1 perturbs histone H2A.Z and the Notch signaling pathway

Elongator dysfunction is increasingly recognized as a contributor to multiple neurodevelopmental and neurodegenerative disorders including familial dysautonomia, intellectual disability, amyotrophic lateral sclerosis, and autism spectrum disorder. Although numerous cellular processes are perturbed i...

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Bibliographic Details
Main Authors: BreAnna Cameron, Elin Lehrmann, Tien Chih, Joseph Walters, Richard Buksch, Sara Snyder, Joy Goffena, Frances Lefcort, Kevin G. Becker, Lynn George
Format: Article
Language:English
Published: The Company of Biologists 2021-09-01
Series:Biology Open
Subjects:
Online Access:http://bio.biologists.org/content/10/9/bio058979