Loss of Elp1 perturbs histone H2A.Z and the Notch signaling pathway
Elongator dysfunction is increasingly recognized as a contributor to multiple neurodevelopmental and neurodegenerative disorders including familial dysautonomia, intellectual disability, amyotrophic lateral sclerosis, and autism spectrum disorder. Although numerous cellular processes are perturbed i...
Main Authors: | BreAnna Cameron, Elin Lehrmann, Tien Chih, Joseph Walters, Richard Buksch, Sara Snyder, Joy Goffena, Frances Lefcort, Kevin G. Becker, Lynn George |
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Format: | Article |
Language: | English |
Published: |
The Company of Biologists
2021-09-01
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Series: | Biology Open |
Subjects: | |
Online Access: | http://bio.biologists.org/content/10/9/bio058979 |
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