Identification and vitro verification of the potential drug targets of active ingredients of Chonglou in the treatment of lung adenocarcinoma based on EMT-related genes

Identification and vitro verification of the potential drug targets of active ingredients of Chonglou in the treatment of lung adenocarcinoma based on EMT-related genes

Lung adenocarcinoma (LUAD) is the main histological type of lung cancer with an unfavorable survival rate. Metastasis is the leading LUAD-related death with Epithelial-Mesenchymal Transition (EMT) playing an essential role. The anticancer efficacies of the active ingredients in Chonglou have been wi...

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Bibliographic Details
Main Authors: Fulai Zhao, Peng Zhao, Junli Chang, Xingyuan Sun, Xiaoping Ma, Binhao Shi, Mengchen Yin, Yongjun Wang, Yanping Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Genetics
Subjects:
lung adenocarcinoma
Epithelial-Mesenchymal Transition
drug targets
active ingredients in Chonglou
bioinformatics
network pharmacology
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2023.1112671/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2023.1112671/full

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