Genome-wide association study finds multiple loci associated with intraocular pressure in HS rats

Genome-wide association study finds multiple loci associated with intraocular pressure in HS rats

Elevated intraocular pressure (IOP) is influenced by environmental and genetic factors. Increased IOP is a major risk factor for most types of glaucoma, including primary open angle glaucoma (POAG). Investigating the genetic basis of IOP may lead to a better understanding of the molecular mechanisms...

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Bibliographic Details
Main Authors: Samuel Fowler, Tengfei Wang, Daniel Munro, Aman Kumar, Apurva S. Chitre, T. J. Hollingsworth, Angel Garcia Martinez, Celine L. St. Pierre, Hannah Bimschleger, Jianjun Gao, Riyan Cheng, Pejman Mohammadi, Hao Chen, Abraham A. Palmer, Oksana Polesskaya, Monica M. Jablonski
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Genetics
Subjects:
genome-wide association study
intraocular pressure
primary open angle glaucoma
heterogeneous stock rats
eQTL analysis
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.1029058/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2022.1029058/full

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