Unique and shared systemic biomarkers for emphysema in Alpha-1 Antitrypsin deficiency and chronic obstructive pulmonary disease

Unique and shared systemic biomarkers for emphysema in Alpha-1 Antitrypsin deficiency and chronic obstructive pulmonary disease

Summary: Background: Alpha-1 Antitrypsin (AAT) deficiency (AATD), the most common genetic cause of emphysema presents with unexplained phenotypic heterogeneity in affected subjects. Our objectives to identify unique and shared AATD plasma biomarkers with chronic obstructive pulmonary disease (COPD)...

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Bibliographic Details
Main Authors: K.A. Serban, K.A. Pratte, C. Strange, R.A. Sandhaus, A.M. Turner, T. Beiko, D.A. Spittle, L. Maier, N. Hamzeh, E.K. Silverman, B.D. Hobbs, C.P. Hersh, D.L. DeMeo, M.H. Cho, R.P. Bowler
Format: Article
Language:English
Published: Elsevier 2022-10-01
Series:EBioMedicine
Subjects:
SomaScan
Protein score
Emphysema
Plasma biomarker
Alpha-1 antitrypsin deficiency
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396422004443

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http://www.sciencedirect.com/science/article/pii/S2352396422004443

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