Dapagliflozin Mitigates Hypotension in Lipopolysaccharide-Induced Acute Inflammation Independent of Glycemia Level

Dapagliflozin Mitigates Hypotension in Lipopolysaccharide-Induced Acute Inflammation Independent of Glycemia Level

Sodium-glucose cotransporter-2 (SGLT2) inhibitors have been suggested to have anti-inflammatory properties in diabetes. The goal of this study was to evaluate the role of the SGLT2 inhibitor dapagliflozin (DAPA) in the attenuation of lipopolysaccharide (LPS)-induced hypotension. Male Wistar albino r...

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Bibliographic Details
Main Authors: Wael A. Alanazi, Turki Alharbi, Doaa M. El-Nagar, Abdullah M. Albogami, Mohammed Alswayyed
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Pharmaceutics
Subjects:
dapagliflozin
lipopolysaccharide
hypotension
inflammation
diabetes
iNOS
Online Access:https://www.mdpi.com/1999-4923/15/6/1683

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https://www.mdpi.com/1999-4923/15/6/1683

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