The Poly-Arginine Peptide R18D Interferes with the Internalisation of α-Synuclein Pre-Formed Fibrils in STC-1 Enteroendocrine Cells

In Parkinson’s disease (PD), gut inflammation is hypothesised to contribute to α-synuclein aggregation, but gastrointestinal α-synuclein expression is poorly characterised. Cationic arginine-rich peptides (CARPs) are an emerging therapeutic option that exerts various neuroprotective effects and may...

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Bibliographic Details
Main Authors: Anastazja M. Gorecki, Holly Spencer, Bruno P. Meloni, Ryan S. Anderton
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Biomedicines
Subjects:
Online Access:https://www.mdpi.com/2227-9059/11/8/2089